TaperMate

Duloxetine capsule combination taper calculator

Combining whole duloxetine capsules — including pharmacy-compounded strengths — lets you build a dose without cutting. Enter the strengths you have and your target below to see the combination.

Duloxetine · combine capsules

Single dose calculator

mg
Dispensed or compounded — comma-separated, e.g. 150, 75, 37.5.
mg
What you want to take today.
Take this combination — exact match
1 × 30 mg + 1 × 10 mg
2 capsules — exactly 40 mg.
Formulacombination dose = sum of the capsules you take
With your numbers1 × 30 mg + 1 × 10 mg = 40 mg
Exact — this combination matches your target
No rounding needed with the strengths you entered.
Keep this calculation Optional
Email this calculation
A record you can bring to your appointment.
Get the plain-English duloxetine guide
How to taper duloxetine safely — we'll email it and the occasional update.

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Combining capsules, step by step

Method The maths above gives the number; these steps are the practical part. Adapted from the RELEASE Toolkit. Adjust the amounts to what your prescriber agreed.
  1. Check which capsule strengths your pharmacy can dispense or compound, and enter them above.
  2. Use the calculator above to find a combination of whole capsules that reaches your target.
  3. Take the combination together as a single daily dose.
  4. Re-check the combination with your prescriber at each reduction step.

About combining capsules

This is just as useful with compounded capsules. If your pharmacist compounds capsules at specific strengths for your taper, enter those strengths here and the calculator works out which combination reaches your target dose — so you can check the numbers and plan what to ask them to make.

Enter the strengths you have on hand and your target dose. If an exact combination exists, the calculator shows it. If not, it shows the two nearest achievable doses — the closest below and the closest above — so you and your prescriber can decide which to use.

Only combine capsules of the same medicine, and never open or split a modified-release capsule to do it. This method works with whole capsules — whether they're standard strengths your pharmacist dispenses or ones compounded specifically for your taper.

Read the duloxetine tapering guidePlain-English steps and the full RELEASE reduction schedule for duloxetine →
Next step

Plan your full taper in TaperMate

This calculator handles one dose. The TaperMate app calculates a full reduction schedule with hold periods, microtapering and symptom monitoring — so each new dose is one tap away, not a daily maths problem.

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Sources to discuss with your prescriber